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I just recently purchased a Mac Pro Intel with Leopard. I was able to install, Coot and ccp4. Both were not as straight forward as I would have hoped but still possible. For Coot: Go to: http://sage.ucsc.edu/~wgscott/xtal/wiki/index.php/Coot-0.5-pre-1-968_for_Intel_10.5_only Download : coot-10.5-pre-1-968-intel-April20_2008.tgz<http://sage.ucsc.edu/%7Ewgscott/xtal/coot/coot-10.5-pre-1-968-intel-April20_2008.tgz> Follow instructions on the page. Beware, when I down loaded it, OSX immediately unzipped it. I am not a guru for OSX, so I just gzipped it prior to running the command: sudo tar xvfz coot-10.5-pre-1-968-intel-April20_2008.tar.gz As you probably experienced, coot wouldn't run at this point. No fear, you will need to install the X11.pkg version 2.20.1. Follow the instructions on the page: http://trac.macosforge.org/projects/xquartz Once you restart the computer, download the CootAutoOpener<http://sage.ucsc.edu/%7Ewgscott/xtal/coot/CootAutoOpener.dmg.gz>. If you placed Coot in the directory as the instructions state, it should run. Note. Tried the CCP4 coot download page and that coot version didn't work. For CCP4: Was a little tricky. I had to get some help on this one for the proper unix commands. Go to the CCP4 site and download the OSX version. Install BOTH the TLK/BLK programs and CCP4 site. Next, I couldn't find anywhere, had to run the following commands in the bin directory to get it to work: source ccp4i.sh # (for bash shell; sets up ccp4's directories, make sure that the paths in this file accurately reflect reality; had an issue here) Then should be able to run: ccp4i When I ran it, I had to source the file every time prior to execution. There may be a better way to do this but I just created an executable script to run it for me. Hope this helps, Scott <http://sage.ucsc.edu/%7Ewgscott/xtal/coot/coot-10.5-pre-1-968-intel-April20_2008.tgz> On Wed, Aug 20, 2008 at 9:33 AM, Paul Emsley <[log in to unmask]>wrote: > Winter, G (Graeme) wrote: > >> I have an OS X leopard machine which I would really like to get coot >> working on, but it appears to involve messing with the X system and / or >> fink, neither of which I really fancy. Now I appreciate that there is >> something broken about the X window (no idea what though) but I was >> wondering if it is possible to get coot working with it anyway? >> I looked at the X window update on Bill Scott's page, but the idea of >> having to reinstall it every time Apple decide to update my machine didn't >> really appeal. >> > > Doesn't Bill provide a stand-alone version? > > If not that then the answer, I think, is "no not yet" - I intend to make > such a thing after returning from IUCr. > > You are not alone. > > Paul. > > -- Scott D. Pegan, Ph.D. Senior Research Specialist Center for Pharmaceutical Biotechnology University of Illinois at Chicago