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Thank you for all the replies,relating to discordant HbA1C and blood glucose results, the suggestions for possible causes were; Increased red cell turnover, due to various causes, including drugs. Slow glycator Hb Constant Springs Variant see www.clinchem.org/cgi/content/full/53/1/142 Alpha lipoic acid used an anti-aging supplement (must get some of this) Suggested follow up includes; blood film, haptoglobin, fructosamine, and variant studies. Can anyone offer a fructosamine assay? Tim. Tim Hogan Laboratory Manager Clinical Biochemistry Basildon and Thurrock University Hospitals NHS Foundation Trust 01268 593036 or 0845 155 3111 Ext 3036 [log in to unmask] <BLOCKED::mailto:[log in to unmask]> www.basildonandthurrock.nhs.uk <http://www.basildonandthurrock.nhs.uk> National Pathology Week 3 - 9 November 2008 ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/