Hello All, I am trying to segment a batch of 66 T1 weighted MR images of the human brain. I would like to run DARTEL on them. When I try to segment the images initially, I get the following error for all 66 images: Warning: Matrix is singular to working precision. > In expm>PadeApproximantOfDegree at 123 In expm at 39 In spm_maff>P2M at 191 In spm_maff>affreg at 152 In spm_maff at 27 In spm_preproc at 152 In spm_config_preproc>execute at 472 In spm_jobman>run_struct1 at 1585 In spm_jobman>run_struct1 at 1595 In spm_jobman>run_struct1 at 1595 In spm_jobman>run_struct at 1514 Error running job: Error using ==> schur Input to SCHUR must not contain NaN or Inf. In file "/usr/local/matlab/toolbox/matlab/matfun/sqrtm.m" (???), function "sqrtm" at line 33. In file "/home/scratch/spm5/spm_maff.m" (v987), function "M2P" at line 160. In file "/home/scratch/spm5/spm_maff.m" (v987), function "affreg" at line 76. In file "/home/scratch/spm5/spm_maff.m" (v987), function "spm_maff" at line 27. In file "/home/scratch/spm5/spm_preproc.m" (v946), function "spm_preproc" at line 153. In file "/home/scratch/spm5/spm_config_preproc.m" (v1032), function "execute" at line 472. -------------------------- Done. What does this error signify and how can I correct it. Thank you. Vidya Rajagopalan Virginia Tech