Dear SPMer
For the
spatial Normalization of image with focal uptake or lesion, cost function masking
should be performed (Ni 14,486-500 (2001))
From the manual
of MRIcro, unified normalization could be done without lesion masking.
Below was
manual on MRIcro homepage
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Normalize
patient MRI scans with MRIcro and SPM5
The best way to normalize images with SPM5 is to use the
unified normalization routine (simply press the 'Segment' button in SPM5). This
option appears to give better solutions than previous versions of SPM or the
standard normalization (which you get if you press SPM5's 'Normalize' button).
Further, it does not appear that lesion masking is necessary if you use the
unified normaliazation with brain lesions (see Crinion et al.
(2007).
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My question is
that
1)
How about PET image
2)
Which option was for unified
normalization in segmentation step?
Actually, I know that spatial normalization was performed in segmentation step.
But, resulting image of segmentation was like probabilistic map.
That means that all count of image was below 1
So which function is for unified normalization with lesion
Best regards
Kim JS