Dear Mayrim,

The reason for the warning you get is simple: in the simulation routines, you have to specify the actual parameters of the model (not just its binary structure).  You entered 1s throughout; with such high rate constants, the system may be unstable, thus the warning (if it actually is unstable over the period of observation can be seen from the graphics output).  Try smaller values (e.g. in the range 0.1-0.5) and the warning should disappear.

Best wishes,
Klaas


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Von: Mayrim Ve <[log in to unmask]>
An: [log in to unmask]
Gesendet: Freitag, den 11. Juli 2008, 14:36:13 Uhr
Betreff: [SPM] Simulate a DCM data

Hello all,

 

We are trying to simulate a DCM data using the same connectivity model presented in DCM paper [1]. We use the spm_dcm_create.m function (SPM5), considering a SNR of 7 and the following parameters:

 

Load factors.mat (it is a file containing the vectors phot, mot and att, which presents information about the onsets of the three applied conditions; it can be obtained in the SPM web page http://www.fil.ion.ucl.ac.uk/spm/data/attention/)

 

 

Enter number of regions [4]

Name for Region 1 [V1]

Name for Region 2 [V5]

Name for Region 3 [PPC]

Name for Region 4 [PFC]

 

Spm_dcm_create: Basic parameters…

Interscan interval {secs} [3.22]

scans per session e.g. 256  [ 360]

Specify design in [scans]

Number of conditions/trials [3]

Name for condition/trial 1? [Photic]

vector of onsets - Photic [phot]

duration[s] (events=0) [10]

Parametric modulation [None]

Name for condition/trial 2? [Motion]

vector of onsets - Motion [mot]

duration[s] (events=0) [10]

Parametric modulation [None]

Name for condition/trial 3? [Attention]

vector of onsets - Attention [att]

duration[s] (events=0) [10]

Parametric modulation [None]

 

Specify intrinsic connections

            -1    1    0    0

             1   -1    1    0

             0    1   -1    1

             0    0    1   -1

 

Effects of Photic           on regions…and connections

V1       1                                  0 0 0 0

V5        0                                  0 0 0 0

PPC     0                                  0 0 0 0

PFC      0                                  0 0 0 0

 

Effects of Motion          on regions…and connections

V1       0                                  0 0 0 0

V5        0                                  1 0 0 0

PPC     0                                  0 0 0 0

PFC      0                                  0 0 0 0

 

Effects of Attention       on regions…and connections

V1        0                                  0 0 0 0

V5        0                                  0 0 1 0

PPC     0                                  0 0 0 1

PFC      0                                  0 0 0 0

 

Then we obtained the following error:

 

“Modelled system is potentially unstable: Lyapunov exponent of combined connectivity matrix is 0.61803”

Check the output to ensure that values are in a normal range.”

 

We´ll appreciate any help about this.

Best regards,

1-       Friston, K.J., Harrison , L. and Penny W. Dynamic causal modeling. NeuroImage 19 (2003) 1273-1302.(please, see figure 24 for more details)

 

 
Mayrim Vega Hernández
Neurostatistica Department
Neuroinformatics subdirection
Cuban Neuroscience Center
Calle 25 esq. 158 Cubanacan, Playa
Havana, Cuba. POBox : 6412,6414
Phones: (53-7) 2717442, (53-7) 2086375




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