In the file selector, the volume to select is usually set to "1". Try setting this to e.g. "1:1000", which will allow you to specify other volumes within the 4D file. Note that if you have *.nii.gz files, you will need to gunzip them first. Best regards, -John On Friday 25 July 2008 05:58, Francis Loayza wrote: > Is possible to use 4D files in SPM ? if the answer is yes, how can I do? > thanks > _________________________________________________________________ > Explore the seven wonders of the world > http://search.msn.com/results.aspx?q=7+wonders+world&mkt=en-US&form=QBRE