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Hi, I'm new with fsl, and have just installed fsl on my Ubuntu. I'm trying to use mfast, have used Bet to extract out non-tissue, but in a most cases, I get the error-message. I'm using mfast on a t1 and a t2 picture. /usr/share/fsl/bin/mfast -s 2 -c 3 -od /media/LaCie/NIFTI-format/Dykkar_Bo_nei/Dykkar_Bo_brain /media/LaCie/NIFTI-format/Dykkar_Bo_nei/Dykkar_Bo_brain /media/LaCie/NIFTI-format/Dykkar_Bo_nei/Dykkar_Bo2_brain.nii.gz No convergence in 30 SVDCMP iterations MFAST - Multispectral FAST Version 3.53 Channel 0: /tmp/fsl_ASbhq4_Dykkar_Bo Channel 1: /tmp/fsl_ASbhq4_Dykkar_Bo2 Imagesize : 256 x 256 x 19 Pixelsize : 0.898438 x 0.898438 x 6.65 Slice is too thick, 2D segmentation will be performed! initial segmentation by KMeans.... 4 main iterations ... Matrix Inverse: Not invertable! Finished In the rest of the cases I get /usr/share/fsl/bin/mfast -s 2 -c 3 -od /media/LaCie/NIFTI-format/Dykkar_Df/Dykkar_Df_brain /media/LaCie/NIFTI-format/Dykkar_Df/Dykkar_Df_brain /media/LaCie/NIFTI-format/Dykkar_Df/Dykkar_Df2_brain.nii.gz 313577.5 681402.9 485882.3 1480862.8 MFAST - Multispectral FAST Version 3.53 Channel 0: /tmp/fsl_5nFAIf_Dykkar_Df_brain Channel 1: /tmp/fsl_5nFAIf_Dykkar_Df2_brain Imagesize : 256 x 256 x 19 Pixelsize : 0.898438 x 0.898438 x 6.65 Slice is too thick, 2D segmentation will be performed! initial segmentation by KMeans.... 4 main iterations ... Segmentation done successfully! Calculation time 51 seconds! Write segmentation image /tmp/fsl_5nFAIf.fastout/QQQQQ_seg.hdr Successfully! Class: tissue 0 tissue 1 tissue 2 total Volume: Finished Do you have any idea what I can do to fix this? I ran the fsl evaluation, and it said that the tests passed. I think maybe there might be something wrong with the brain extraction, cause when I tried to use an another computer with mfast, it all worked out fine. Thanks, Hege