All the image will be used together to get the best estimates - if you enter multiple b=0 images it will have the equivalent effect to averaging your b=0 images You can put any volumes at any point in the data, as long as each element in bvecs/bvals refers to the correact volume of data. Hope this helps T On 25 Jun 2008, at 08:01, Hanne Antila wrote: > Hello, > > I was wondering what bedpostx does if it encounters multiple > volumes with > same vector directions, for example multiple b0 -images? Will there > be some > averaging, will just one volume be chosen for analysis or will all the > volumes be analysed? > > I have understood that all the b0 images have to be in the > beginning of the > 4D data -file, is this correct? > > I will be grateful for all the help! >