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R. Michael Garavito, Ph.D.
Professor of Biochemistry & Molecular Biology
513 Biochemistry Bldg.
Michigan State University
East Lansing, MI 48824-1319
Office: (517) 355-9724 Lab: (517) 353-9125
FAX: (517) 353-9334 Email: [log in to unmask]
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Hi:Just a related question. To measure MW of membrane proteins, the densityof detergents needs to be matched by D2O/H2O and should be within 1.0 to1.1. Anyone knows some literature that gives a list of detergents havingsuitable density? Unfornatatedly, the common ones like Foscholine 12(DPC)and C12E9 do not work with my protein.Regards,WeikaiHi Mike,try the National Analytical Ultracentrifugation Facility in Connecticut.Cheers, PetraDear colleagues,does anyone know of a faciltiy for analytical ultracentrifugation?Thanks.Mike Colaneri--Petra Verdino, PhDResearch AssociateThe Scripps Research Institute, BCC20610550 North Torrey Pines RoadCA 92037 La Jolla, USAtel:1-858-784-2945fax:1-858-784-2980