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Dear Colin > I have a question about Karl Friston’s 1997 paper “ > Testing for Anatomically Specified Regional Effects.” I was > wondering if anyone has created code to implement the correction. > This correction is ideal given our data, but I’m unsure about > how to go about implementing the correction myself. The problem is, > as mentioned in the paper, that our functional activation is > approximate to the anatomically predefined area of interest but is > not completely within this region. However, a whole brain correction > is too stringent, and seems inappropriate in this case. You are looking for a 'small volume correction', i.e. exploring the activation in an a-priori defined area. That option is in fact implemented in SPM. When exploring the results, you should move the pointer to the area of interest (or use a predifined a mask) and use the 'S.V.C.' (SPM2) or 'small volume' (SPM5) button. Good luck, Karsten -- ------------------------------------------------------------- Karsten Specht, PhD Department of Biological and Medical Psychology & National Competence Centre for functional MRI University of Bergen Jonas Lies vei 91 5009 Bergen Norway Tel.: +47-555-86279 Fax: +47-555-89872 [log in to unmask] http://fmri.uib.no/