Hi all, This is in some ways related to a problem Justin posted about last summer with regard to transposing XY planes to ZY planes, although in my case I want to keep the XY view and open another window for the ZY view to help me resolve degeneracies in my spectra. I didn't find an answer to the problem on the forum, but may have missed it. The long and short of the problem is, when I try to open a ZY window, Analysis essentially takes over my computer until it runs out of memory and crashes. Trying to create a contour file for the (2,3) dimension has the same problem, as does creating a new project, making a (15N,13C) window with 1H on the Z-axis, and then trying to open the spectrum. For what it's worth, the spectrum in HNCACB with moderate S/N, and the processed NMRPipe spectrum file is ~800 MB on disk. My gut feeling is that there is some sort of issue with contouring in this dimension. Even if I set the contour level up an order of magnitude relative to the "normal" view (which works fine) and then try to make a contour file, the file just keeps growing (I aborted at > 1 GB, the "normal" contour file is ~2.4 MB). I'm running Analysis (upgraded via the menu late last week) on a 2 GHz Core Duo iMac with 2 GB of RAM. It was compiled using Python 2.4. Activity Monitor shows Python grabbing <99% CPU (expected during contouring and not problematic in and of itself), and also disturbingly shows the memory used by python (i.e. analysis) growing until it grabs well over 1.6 GB of real RAM plus virtual memory in excess of 12 GB before it finally crashes. Messages from analysis are: >>> python(287) malloc: *** vm_allocate(size=1069056) failed (error code=3) python(287) malloc: *** error: can't allocate region python(287) malloc: *** set a breakpoint in szone_error to debug Drawing canvas tile ContourFile error: allocating contour memory python(287) malloc: *** vm_allocate(size=1069056) failed (error code=3) python(287) malloc: *** error: can't allocate region python(287) malloc: *** set a breakpoint in szone_error to debug Drawing canvas tile ContourFile error: getting xextended block data python(287) malloc: *** vm_allocate(size=1069056) failed (error code=3) python(287) malloc: *** error: can't allocate region python(287) malloc: *** set a breakpoint in szone_error to debug Drawing canvas tile ContourFile error: getting xextended block data python(287) malloc: *** vm_allocate(size=1069056) failed (error code=3) python(287) malloc: *** error: can't allocate region python(287) malloc: *** set a breakpoint in szone_error to debug unable to alloc 144d bytes /usr/local/ccpnmr/bin/analysis: line 8: 287 Abort trap /sw/bin/python -i -O $CCPNMR_TOP_DIR/ccpnmr1.0/python/ccpnmr/analysis/AnalysisGui.py $1 $2 $3 $4 $5 The final message is when the program crashed. Any suggestions/solutions will be greatly appreciated. Cheers, Andrew Notice: This UI Health Care e-mail (including attachments) is covered by the Electronic Communications Privacy Act, 18 U.S.C. 2510-2521, is confidential and may be legally privileged. If you are not the intended recipient, you are hereby notified that any retention, dissemination, distribution, or copying of this communication is strictly prohibited. Please reply to the sender that you have received the message in error, then delete it. Thank you.