Print

Print


Hi Matthew,

 

Thanks for your reply.  Here is an example commandline applied to a T1 image:

 

fast4 -b -o default T1Struct

fslmaths T1Struct -mul default_bias T1Struct_default

fast4 -b -I 8 -o I8 T1Struct

fslmaths T1Struct -mul I8_bias T1Struct_I8

fast4 -b -I 12 -o I12 T1Struct

fslmaths T1Struct -mul I12_bias T1Struct_I12

 

The files T1Struct_default T1Struct_I8 T1Struct_I12 are all the same.  If I run the default, and then run the default again on the restored image I get a different (somewhat better) result.  Also, what are the units of the --lowpass and ---Hyper smoothing options?

 

Thanks,

 

Matt.

 


From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On Behalf Of Matthew Webster
Sent: Monday, April 07, 2008 6:39 AM
To: [log in to unmask]
Subject: Re: [FSL] Fast4 Question

 

Hi,

     We've done some tests with fast4 and we can't replicate what you've seen with an invariant bias field for different --iter. Could you go into more detail into the method you've used ( specific command lines etc)? Given the smaller brain size you may want to lower the --lowpass and ---Hyper smoothing options...

 

Many Regards

 

Matthew

I have found that running fast4, restoring the image with the bias field, and then rerunning fast4 several times gives a better estimation of the bias field than just running fast4 a single time.  I tried to duplicate this by increasing the number of main-loop iterations during bias-field removal (the --tier option) from 4 to 8, for example, but this gave exactly the same result for the bias field restoration.  How would I get the same improvement in bias field estimation without rerunning the program several times (and wasting time calculating segmentations that I don’t plan to use)?  Also, are there any settings I should change for non-human primates with their smaller brains?  It seems like sulci are often smoothed out of the segmented image.

 

Thanks,


Matt.