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Hi, You could use fslmaths to label only this voxel with a 1 (everywhere else 0) in a mask image and then use distancemap to fill the mask out with values of distance from that voxel and then in fslmaths multiply that by the activation cluster and then find the lowest value in the intersection. Steve. On 10 Apr 2008, at 20:05, Marc Dubin wrote: > Dear FSL Users, > > I have noticed when using the *cluster* function that it often picks a > non-significant voxel as the centroid of a given cluster. Does > anyone know > of an option that will return the closest significant voxel as the > centroid? > > Sincerely, > Marc > --------------------------------------------------------------------------- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ---------------------------------------------------------------------------