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We’ve seen a huge increase in numbers here at Guys – probably a 10 fold increase and, significantly, the majority are positive. A few weeks ago, we were analyzing ethylene glycols every day of the week, occasionally up to 7 different samples per day.

 

Its certainly keeping us busy at the moment, as if we didn’t have enough to do!

 

Kind regards

 

David Gerrie

 

Guys & St Thomas Medical Toxicology Laboratory

London

 

-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Colley, Michael
Sent: 15 April 2008 15:39
To: [log in to unmask]
Subject: Re: ethylene glycol

 

I posted this on the Mail list on 4th February, just a couple of days after the news hit the papers.  Guys told me they'd seen a major surge in numbers over the few days after that.   I'm please to say we haven't had another...yet.

 

Michael

 

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Further to Jonathan Kay's email re. the "Antifreeze" case, I'm delighted to report that our first Ethylene Glycol overdose for many years presented at 10:30 on Thursday morning.  Despite having apparently drunk about 700 ml of it he seems to be reasonably well at present.

 

He had an osmolar gap of well over 20 mosmol/L and his Glycol level was 2g/L.  Dialysis is recommended at >0.5 g/l.

However, as he appeared well, dialysis was not carried out and he was treated with fomepizole.

 

Appears to have survived very well and was transferred from ICU to the ward yesterday.

 

Will keep you updated if anything further of interest arises.

 

How many people do EtOH levels by a non-GC (i.e. enzymatic) method?  As we don't it couldn't be monitored regularly which is why he received fomepizole rather than EtOH infusion.

 

Michael

 

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