Hi Stefano, I can't clearly understand your question, but think this might be the answer you are looking for TFCE image is not like z_stat image for which you have a default null distribution, so you need to have your null distribution generated and do a (voxel-wise) non-parametric test to assess the statistical significance of your image, one way of doing it is to use randomise and making the distribution of max_tfce over each fake image and then calculating the p-value for each voxel in your observed (real) image, Best, Reza On Thu, Mar 27, 2008 at 5:30 PM, Marenco, Stefano (NIH/NIMH) [E] < [log in to unmask]> wrote: > I got an image of the tfce statistic with fslmaths. How do I transform > this to a p value image (from tfce_tstat to _*max_*tfce_tstat)? > > > > *Stefano Marenco**, MD* > > NIMH/GCAP > > Building 10, room 4S235 > > 10 Center Drive > > Bethesda, MD 20892 > > tel 301 435-8964 > > fax 301 480-7795 > > email: [log in to unmask] > > > -- G. Salimi-Khorshidi, DPhil Student in Oxford Centre for Functional MRI of the Brain (FMRIB) Dept of Clinical Neurology, University of Oxford webpage : http://bme.aut.ac.ir/~gsalimi <http://bme.aut.ac.ir/%7Egsalimi> email : [log in to unmask]