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Hello, When I click on 'Apply' in the Directories & Project Directory window, I get the following error: ERROR saving parameters to file /Users/Kat/.CCP4/unix/directories.def > Has anyone else encountered this error? I installed CCP4 on a MacBook Pro running Leopard using fink. This error always occurs, except in one mysterious instance today, but only to hang in refmac. I checked, but there is no .CCP4 folder in '/Users/Kat/'. When I tried to create one myself, OS X wouldn't allow me to do so according to some rule that folder names can't begin with periods. I am getting the impression that CCP4 is buggy on OS X. Any information on avoiding these problems and getting CCP4 to work? Thank You, Kurt Padilla on the behalf of: Kathleen Frey Amy Anderson Lab Dept. of Pharmaceutical Science University of Connecticut