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This may or may not be a relevant consideration in previous mailing last week : NICE guideline for Chronic Kidney Disease - consultation open From Robert Hill on behalf of the ACB Scientific Committee with best wishes Richard Richard Mainwaring-Burton Consultant Biochemist Queen Mary's Hospital Sidcup, Kent 020-8308-3084 -----Original Message----- From: Victoria Clough [mailto:[log in to unmask]] Sent: 17 March 2008 13:31 To: [log in to unmask] Subject: Usefulness of PTH in assessing vitamin D status We have noticed a significant increase in the number of requests we are receiving for 25OHD and are trying to establish whether it is always necessary to measure 25OHD itself or if PTH can be used as a first line test, with 25OHD being measured only if the PTH is raised. I've come across a couple of papers which recommend the above approach but have also read several which suggest that PTH is no substitute for 25OHD as it can be normal in vitamin D deficiency and shows poor correlation with 25OHD, with the relationship between the 2 analytes varying with age. It would be useful to know the approach taken by other labs and I'd be grateful for any references which decisions have been based on. Thank you Victoria Clough Pre-Registration Clinical Biochemist King George Hospital, Goodmayes ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/