On Feb 11, 2008 5:08 PM, Jeff Browndyke <
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wrote:
Is
there a way to calculate an adjusted statistical threshold for an analysis
outside of SPM given a stated p-value threshold (i.e., p < .01,
uncorrected), extent threshold [k > 20 (40mm3)], and known voxel number for
the analysis?
SPM uses the smoothness of the noise and the topology of the search
region to determine corrected P-values. Hence to duplicate the inferences
outside of SPM you'd have to have the complete RESEL count vector available, as
stored in SPM.xVol.R in SPM.mat
If approximate inference is sufficient,
and you know at least the FHWM of the noise smoothness, the snippet below will
give you some idea of the corrected P-value for a given FWHM, assuming a
spherical search region of a given radius. More accurate P-values will be
had by reading the help on spm_resels and specifying a more accurate search
region, and, most accurately, using the RESEL vector from SPM.xVol.R of the
relevant SPM results.
-Tom