Dear Tobias, Good to hear that you are enjoying your new life at Princeton! I hope you have had a good start. There are two ways in which you could proceed without having to re-estimate your GLMs: 1. For each subject, you could combine the parameter estimates across sessions using the "average" function in DCM. For each parameter estimate, this will give you a weighted mean across sessions (weighted by the session-specific posterior variances). You could then feed the resulting values into a classical second level analysis (e.g. t-test). 2. You can account for the dependency amongst the parameter estimates within each subject by using a repeated measures ANOVA ("repeated measures" because you have multiple parameter estimates for each subject, i.e. one for each session). All the very best, Klaas ----- Ursprüngliche Mail ---- Von: Tobias Overath <[log in to unmask]> An: Klaas Stephan <[log in to unmask]> Gesendet: Dienstag, den 12. Februar 2008, 17:18:57 Uhr Betreff: DCM with multiple sessions Hi Klaas, I hope you are enjoying your life together in Zurich - I am very happy here in Princeton, sharing life with Lillian at last. I have a hopefully quick question regarding multiple sessions in DCM. I understand one way is to concatenate the session (and introduce session constants etc.); however, I would rather avoid that (mainly for time reasons, i.e. having to re-estimate the GLMs). Instead, I have estimated each model for each session separately (e.g. DCM_model1_sess1, DCM_model1_sess2, DCM_model1_sess3, DCM_model1_sess4). I have searched in the SPM archives and in your Powerpoint slides to find a way how to combine the different session DCMs of the same model? Or would you suggest I bite the bullet and re-estimate my GLMs with concatenated sessions? Best, Tobias Heute schon einen Blick in die Zukunft von E-Mails wagen? Versuchen Sie´s mit dem neuen Yahoo! Mail. www.yahoo.de/mail