Ian,
CSF ferritin is massively raised in siderosis. We use a reference range
of <12 ug/L derived from CSF obtained from patients in our institution
where no pathology had been demonstrated.
Ian
Dr Ian D Watson
Consultant Biochemist
Dept Clinical Neurobiochemistry
The Walton Centre for Neurology & Neurosurgery
Lower Lane
Liverpool
L9 7LJ
Tel +44 151 529 3575 (office)
+44 151 529 5577 (lab)
Fax +44 151 529 3310
________________________________
From: Clinical biochemistry discussion list
[mailto:[log in to unmask]] On Behalf Of Woodrow Iain
Sent: 06 February 2008 12:35
To: [log in to unmask]
Subject: CSF ferritin and iron for superficial siderosis
Hi all,
Does anyone have any experience in measuring ferritin and iron in CSF to
investigate for superficial siderosis? We have a request for this in a
patient who has an apparently equivocal MRI scan, with a previous
history of surgical brain procedures (a predisposing factor). I can find
very little about it in an, albeit brief, literature search, though one
paper from presented two cases where the CSF ferritin was greatly
elevated (values of 90 and 31 respectively, with a reference range of
<12ug/L, though no indication from where this was derived).
I have tried Sheffield and Leeds in our locale, plus Queen's Sq in
London.
Thanks in anticipation,
Iain Woodrow
Dr I Woodrow,
Clinical Scientist,
Pinderfields Hospital,
Wakefield
------ACB discussion List Information-------- This is an open discussion
list for the academic and clinical community working in clinical
biochemistry. Please note, archived messages are public and can be
viewed via the internet. Views expressed are those of the individual and
they are responsible for all message content. ACB Web Site
http://www.acb.org.uk List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions
(How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List
Information-------- This is an open discussion list for the academic and
clinical community working in clinical biochemistry. Please note,
archived messages are public and can be viewed via the internet. Views
expressed are those of the individual and they are responsible for all
message content. ACB Web Site http://www.acb.org.uk List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions
(How to leave etc.) http://www.jiscmail.ac.uk/
************************************************************************
*******
This email is confidential and intended solely for the use of the
individual
to whom it is addressed. Any views or opinions presented are
solely those
of the author and do not necessarily represent those of the
Organisation. If
you are not the intended recipient, be advised that you have
received
this email in error and that any use, dissemination, forwarding,
printing
or copying of this email is strictly prohibited. If you have
received this
email in error please notify the sender. This e-mail has been
checked
for viruses using anti-virus software
*******************************************************************************
This email is confidential and intended solely for the use of the individual
to whom it is addressed. Any views or opinions presented are solely those
of the author and do not necessarily represent those of the Organisation. If
you are not the intended recipient, be advised that you have received
this email in error and that any use, dissemination, forwarding, printing
or copying of this email is strictly prohibited. If you have received this
email in error please notify the sender. This e-mail has been checked
for viruses using anti-virus software
------ACB discussion List Information--------
This is an open discussion list for the academic and clinical
community working in clinical biochemistry.
Please note, archived messages are public and can be viewed
via the internet. Views expressed are those of the individual and
they are responsible for all message content.
ACB Web Site
http://www.acb.org.uk
List Archives
http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html
List Instructions (How to leave etc.)
http://www.jiscmail.ac.uk/
