 |
 |
Dear Luca, You're after a kind of SISCOM analysis, right? To make any statistical inference, you have to have some variance, but you don't have between-subject variability with just two images. The SISCOM "trick" is to derive the variability between voxels (and within subject). So you need to coregister your images; intensity normalise them; derive the distribution of differences across voxels (normally involving some kind of masking or thresholding); and then threshold the statistical output. If you have access to Analyze from the Mayo, there's now a button that guides you through it all step-by-step. If not, you could use many kinds of imaging software for it, including probably SPM2 or MRICro(n). Terry J O'Brien has worked a lot on it - maybe they've got specific software too. Hope this helps, Alexander -----Original Message----- From: SPM (Statistical Parametric Mapping) [mailto:[log in to unmask]] On Behalf Of Luca Bellesi Sent: 18 January 2008 10:54 To: [log in to unmask] Subject: [SPM] ictal vs interictal single subject hy, i'm a new user of SPM2 and i've a question: is possible to subtract the interictal spect image VS the ictal of the same subject with SPM2, to see the significant voxel, without compare with the healthy normal database?(simple subtraction of interictal and ictal spect) if it is possible please explain with details the procedure in SPM2, beacouse i've tried to do this but i didn't find a solution. i give my email adress: [log in to unmask] thanks