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I'm afraid I can't figure out the cause of this problem. Did you reslice after aligning, or just align? Maybe do a reslicing as well. That's all I can think of that may help. Best regards, -John > I'm beginning to explore the technique of deformation-based morphometry. I > have longitudinal T1 images from the same subject. I've performed > preprocessing on the images including resetting the origin, skullstripping, > and registering (aligning) the later scan to the earlier scan. When I try > to run high dimensional warping on the images in SPM5, however, I get the > following output: > > Initialising SPM.........done > > SPM present working directory: > /Users/neurolabII/Desktop/newly_processed_scans/80 > -------------------------- > Running "High-Dimensional Warping" > Generating uniform affine transformation field > Warping (iterations=8 regularisation=4) > 9.9772625 > nan > XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX > > The program keeps printing "Xs" and I have to force quit Matlab. I am able > to use the SPM2 deformations utility on these images, however, and obtain a > jacobian determinant image (jy_*). Any idea why I am having this trouble > with SPM5, but not SPM2? Is there any advantage of SPM5 over SPM2 for high > dimensional warping? Thanks in advance for any insights you may be able > to offer. > > -Lynne