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Hi FSLers, I have a question, if I am using randomise to analyze an ANOVA type design, do I need to include a design.grp file for my two groups? I want to look at differences in pre and post and differences in sick and not sick... And if so, how should it look because I keep getting an error when I try to run randomise with the design.grp file and the design.fts file...I have checked the number of rows etc and they match my datapoints... group.datis not a valid vest file terminate called after throwing an instance of 'RBD_COMMON::BaseException' Aborted I get the same message when I try to make a F test file... design.grp %! VEST /NumWaves 1 /NumPoints 10 /Skip /PPheights 1 1 /Matrix 1 1 1 2 2 1 1 1 2 2 Thanks! Kelly Brown UCHSC Research Fellow