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Hi, There is currently not a general robust script that works well in a wide range of lesion images I'm afraid. It is often possible to tweak FAST/FAST4 to multiple channels to get good segmentations (e.g. asking for 4 classes), but nothing that works all the time - partly, for example, because FAST uses a histogram mixture model which then gets unhappy if there are very few lesion voxels. This is something that we will be working on, using a more custom approach to the problems, but nothing right now - sorry. Cheers, Steve. On 17 Jan 2008, at 17:11, Ruchika Wadhwa wrote: > Hi, > > After looking through the posts on lesion load analyses, I came > across this one that mentioned that > you were in the process of developing a t2-lesion script that would > use T1 and T2 images to > calculate lesion load. > I was wondering if there is a beta version of that script that could > be used? If not, are there any other > ways to calculate lesion load and to segment the images into gray, > white, csf and lesion volumes? > > Thanks, > -Ruchika. > --------------------------------------------------------------------------- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ---------------------------------------------------------------------------