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I need to organise a penicillamine challenge test for a patient with
probable Wilson's disease there are lots of references to this test on
the net but they all give instructions like this:
Following penicillamine 0.5 g 12 hourly x 2, urine copper exceeds 25
micromol/24 hour in 88% patients with WD and 2% with other liver
disorders.
Does anyone know the precise time schedule relating the penicillamine
should be taken and the time the urine collection starts?
i.e. is it start both penicillamine and collection at the same time, or
is there a lag between taking the drug and starting th eurine
collection?
TIM
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Prof. Tim Reynolds,
Queen's Hospital,
Belvedere Rd,
Burton-on-Trent,
Staffordshire,
DE13 0RB
work tel: 01283 511511 ext. 4035
work fax: 01283 593064
work email: [log in to unmask]
home email: [log in to unmask]
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