All,

 

Further to my recent query regarding evidence of fluid crystal stability in synovial fluid samples, below is a summary of a short study conducted on a mixture of positive crystal samples.

 

We looked at five synovial fluid samples from a variety of collection sites – samples kept in the fridge and fresh aliquot used for each analysis.

 

 

CRYSTALS	DATE CRYSTALS SEEN
Calcium pyrophosphate	17/7 and 20/7
Urate	19/7 and 24/7
Urate	31/7 and 2/8
Calcium pyrophosphate	2/8 and 7/8
Urate	2/8 and 7/8

We did not observe any gross deterioration of urate or calcium pyrophosphate during this short study period.

 

Thanks for all correspondence regarding this query.

 

Colin Stone                   [log in to unmask]

Louise Alexander           [log in to unmask]

 

Clinical Biochemistry Dept.

Kings College Hospital NHS Foundation Trust