The variability of the origins is definitely the problem, and probably relates to your conversion software including something in the headers that confuses SPM (eg it may put some other info in the field that SPM uses for the origin). If you have DICOM data, then the DICOM conversion within SPM may work for your data. Best regards, -John -----Original Message----- From: SPM (Statistical Parametric Mapping) [mailto:[log in to unmask]] On Behalf Of Jamil Zaki Sent: Thursday, August 09, 2007 12:04 AM To: [log in to unmask] Subject: [SPM] Realignment error spm2 Hi All -- I've searched the archives for this topic, but can't find much information on it. I'm getting an error I haven't seen before when attempting to realign my functional images (error pasted below). When looking at multiple images with check_reg, I notice that they have very different origins (and that the numbers that are part of the origin seem strange), and think this might be part of the problem. Could this have occured due to problems converting from the original dicom images? Does anyone know about a solution to this? Thanks very much for any help, Jamil * - SPM2: spm_realign --------------------------------------------- There is not enough overlap in the images to obtain a solution. Offending image: /Volumes/Brainiac/Emp_Acc_fMRI/s01/funs/e1/vols0002.img Please check that your header information is OK. ----------------------------------------- 17:56:12 - 08/08/2007 ??? Error using ==> spm_realign>error_message insufficient image overlap