Dear SPMer: I have a basic question for the contrast definition. If there is only 1 task (left hand tap, eg.), resting as control state. then, how will I enter the number in the Number of conditions/trails in the model speification. 1 or 2 ? And, in the RESULT step, how will I enter the number in the window of contrast manager ? 1 -1 0, or 1 0 0 (conditions=2). what the differences between 1 0(1 condition), 1 -1 0 and 1 0 0(2 conditions)? In the contrast manager, the sum of the definition values must be 0 ? Someone told me that the result of "1 -1 0(2 condition)" was better than that of "1 0 (1 condition)". But I compared them and found the activation of "1 0 (1 condition)" was stronger than "1 -1 0(2 condition)". What's the reason? In the above example which have only 1 actual task, if the correct specification number is "2" , I wonder why SPM permit "1", "2" will be the minimum number in the model specification? Thanks a lot! Zhiqiang Zhang Nanjing University , China. --------------------------------- ÑÅ»¢Ãâ·ÑÓÊÏä3.5GÈÝÁ¿£¬20M¸½¼þ£¡