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Yes even I was wondering why it was posted to this list. rakesh On 7/21/07, k.hopayian <[log in to unmask]> wrote: > > This looks like a commercial posting. It does not add to the discussion on > EBP, add to our understanding of it or ask/contribute to collaboration. I > would like to know what others on this list think about such postings. > > > -- > B/W, Kev Hopayian > -------on 20/7/07 11:14, Jane McHugh at [log in to unmask] wrote: > > *Evidence still lacking on how fast antidepressants act* > > One of the most important questions about antidepressant drugs - how > quickly they act - remains unanswered, say mental health experts today. > > In an editorial for BMJ Clinical Evidence, Andrea Cipriani and colleagues > say that the speed people respond to these drugs has great clinical > relevance for both the patient and the physician, but conclusive evidence is > still lacking. > > For instance, a shorter response time rapidly improves patient wellbeing, > decreasing length of hospitalisation, and reducing the amount of time the > patient spends away from work, and the time the impairment affects family > and friends. It also enables physicians to make prompt decisions about > changing or optimising treatment. > > Views have changed over the years, but recent studies indicate that these > drugs act quickly rather than having a delayed effect. > > However, there are many challenges involved in designing studies to detect > timing of onset, say the authors. For example, how to measure and define an > early response and what degree of symptom reduction is needed to fulfil this > definition. > > They also point to financial incentives surrounding fast acting > antidepressants, and warn clinicians to ensure that fast onset of action is > not valued at the expense of tolerability or long-term effectiveness of > antidepressant treatment. > > Ends > * > Note to editors:* > BMJ Clinical Evidence is an international peer reviewed medical journal, > published by the BMJ Group. In addition, BMJ Clinical Evidence provides an > invaluable set of evidence based medicine facilities to help busy clinicians > manage their patients as effectively as possible. It sums up what's known - > and not known - about more than 3000 interventions and 540 clinical > questions and is one of the world's most trusted and effective sources of > medical evidence for clinical decisions. > > Further information from: > Shannon Amoils, Clinical Editor, BMJ Clinical Evidence > Tel: 0207 383 6737 > Email: [log in to unmask] > *www.clinicalevidence.co.uk* <www.clinicalevidence.co.uk > www.clinicalevidence.co.uk> > > Click here to view full editorial: * > http://press.psprings.co.uk/bmj/july/Cipriani.doc* > <http://press.psprings.co.uk/bmj/july/Cipriani.doc><http://press.psprings.co.uk/bmj/july/Cipriani.doc> > > > > > > > > > > > ---------------------------------------------------- > Jane McHugh, Information Specialist > BMJ Knowledge, BMJ Group > BMA House, Tavistock Square, London WC1H 9JR > Tel: 020 7383 6384 Fax: 020 7383 6242 > > http://www.clinicalevidence.com > http://www.besttreatments.co.uk > > > ********************************************************************** > This email and any files transmitted with it are confidential and > intended solely for the use of the individual or entity to whom they > are addressed. If you have received this email in error please notify > [log in to unmask] > > ********************************************************************** > _______________________________________________________________________ > > This email and any attachments are confidential and intended solely for > the addressee. They may not be disclosed to, used by or copied in any way by > anyone other than the intended recipient. If you have received this email in > error please notify [log in to unmask] and delete the email > transmission immediately. > > Any views expressed in this email are those of the individual and may not > represent those of the BMJ Publishing Group Ltd. > > Computer viruses can be transmitted by email. The recipient should check > this email and any attachments for presence of viruses.The BMJ Publishing > Group Ltd accepts no liability for damage caused by any virus transmitted by > this email. Emails sent or received by the BMJ Publishing Group are > monitored. > > BMJ Publishing Group Limited > A private limited company, registered in England and Wales under > registered number 03102371 > Registered office: BMA House, Tavistock Square, London WC1H 9JR, UK. > http://bmjgroup.bmj.com > _______________________________________________________________________ > > > > > >