Hi, Yes this is a tricky image to segment - for example, fast -t2 N00001_brain gives an ok segmentation if you consider merging two of the output classes into one CSF class - but there is confusion between CSF and cortical gray. As this is such an unusual image I would recommend a more custom approach. You can choose an intensity threshold by hand and use avwmaths++ and avwstats++ to estimate CSF volume. I wouldn't recommend trying to use SiENAX as the ventricles won't match the standard space masks well. Cheers, Steve. On 20 Jun 2007, at 17:37, Flavio Dell'Acqua wrote: > Hi > > I have uploaded data with also an updated snapshot (using also -l > 10000) ID: 187779 > > We have tried with -l1000 and -c 2 as suggested. We get an > improved CSF segmentation but not in the center of ventricles. > In this area, in the restored data, after bias correction, > artifactual signal attenuation remains. > > Few minutes ago we finished a -l5000 and -c 2 and now we have a > correct CSF segmentation also in ventricles! > Vetricles are very huge and looking at these results I think there > is now a problem with the ventricles > mask used by sienax/fast...but this is the next step. :-) > > just a question: -c 2 is compatible with -r option in > sienax ? ...we are only interested in CSF and ventricle CSF > quantification. > > > flavio > > Steve Smith ha scritto: >> Hi - thanks for sending the results snapshot, though really we >> would need to see the data to get a better idea of what's going on. >> However, from looking at the snapshot, your ventricles are huge, >> and the grey-white contrast is very poor, so this may be hard. You >> may get much better results with just asking for 2-class >> segmentation (-c 2) and then the bias estimation should work fine >> anyway hopefully. >> Cheers, Steve. >> > > > > ******************************************************************** > Sostieni la ricerca del San Raffaele con il 5permille! > E' SEMPLICE E NON COSTA NULLA. > Basta indicare nell'apposito riquadro della dichiarazione dei > redditi ("Ricerca sanitaria") il codice fiscale della Fondazione > Centro S. Raffaele del Monte Tabor: > 03 06 42 80 153 e ricordarsi di firmare. > Se vuoi saperne di piu' scrivi a [log in to unmask] o vai sul sito > w w w . 5 x m i l l e . o r g ------------------------------------------------------------------------ --- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ------------------------------------------------------------------------ ---