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Dear all, Please see below details of the next meeting of the Royal Statistical Society primary health care study group. There is no charge an no need to book. Everyone welcome. Best wishes Sandra PRIMARY HEALTH CARE STUDY GROUP programme Wednesday 27th June 2007 Royal Statistical Society, Errol St, London 2-5pm (directions http://www.rss.org.uk/about/direction.html) No pre-registration is necessary Systematic Reviews in Primary Care 2pm KEITH ABRAMS (University of Leicester) and LAURA KOOPMAN (University Medical Center Utrecht) Development of Systematic Review Methods in a Primary Care Context Although the use of systematic review methods (including meta-analysis) is often of relevance in primary care, there are a number of methodological issues which arise. We discuss specifically the synthesis of methodologically heterogeneous studies with respect to design (including cluster RCTs and observational studies), and the use of Individual Patient Data (IPD) and subgroup analyses. 2.25pm STEPHANIE TAYLOR (Barts and The London, Queen Mary's) Conundrums arising from a Systematic Review of a Complex Self Management Intervention Complex interventions in health care are non-pharmacological interventions "made up of various interconnecting parts" (Campbell 2000). Trials of complex interventions are increasingly becoming the subject of systematic review and meta-analysis but the findings of such systematic reviews are often difficult to interpret or implement. We describe some of the methodological challenges encountered in the meta-analyses performed for a Cochrane systematic review of lay led self management education for patients with chronic conditions. 2.50pm RAFAEL PERERA (Oxford University) Self-monitoring (SM) for Oral Anticoagulation Therapy (OAT) SM for OAT reduces the odds of death, thrombosis, and major haemorrhage. However, there is uncertainty if this reduction depends on the type of care used in the control group (specialised clinic or general/family practice); with better care provided to the control group translating into a smaller reduction. I will present results from a systematic review of SM for OAT comparing general practice with specialised care in the management of oral anticoagulation. 3.15pm Tea 3.45pm Discussion in groups 4.30pm Rounding up and conclusion Sandra Eldridge Reader in Medical Statistics Centre for Health Sciences Queen Mary, University of London Abernethy Building 2 Newark Street Whitechapel London E1 2AT tel: 020 7882 2519 fax:020 7882 2552 PA: Diana Browne 020 7882 2503