Dear SPMers: I have a coordinate [x,y,z] in 3D image 'abc.img'(with [0 0 0] as orgin in abc.hdr, dimension [101 111 121]), I want to know it MNI coordinates. I coregistered 'abc.img' to 'T1.mnc', then I got the .mat file (let us say, 'abc.mat'). I get transformation matrix ABC (4*4) from 'abc.mat'. Does my MNI coordinate suppose to be ABC * [x-101/2 , y-111/2, z-121/2, 1]' ? Could you please tell me where is wrong? Thank you very much! Weiying ____________________________________________________________________________________Choose the right car based on your needs. Check out Yahoo! Autos new Car Finder tool. http://autos.yahoo.com/carfinder/