Dear Christian, Thank you. It is introduced that betfunc uses a -f 0.3 for 4D fmri data while I found bet in Melodic uses a -f 0.4. Bet in melodic cut off the most top slice of my data but betfunc didn't. I think it is better for my data to use betfunc first then pass the mask made to melodic explicitly, as you said. Regards, wei Christian Beckmann <[log in to unmask]> дµÀ£º Hi melodic uses a different approach to robustifying bet for 4D data. In betfund, the inital mask is generated from the first image and then dilated by 1 voxel in x,y and z before masking all volumes by this new dilated mask. In melodic the bet outline is found by running bet on the mean image across time. I have not evaluated the differences explicitly but guess that they are small. Note that you can always pass a mask to melodic explicitly by using the -m option cheers christian On 23 May 2007, at 15:49, pengxu wei wrote: > Dear list, > > I have read some message in the archive but no answer available. > betfunc is better than routine bet for 4D fmri data, so whether bet > in Melodic is betfunc(when using GUI or command line), or just > routine bet? > > Regards, > > wei > > ÇÀ×¢ÑÅ»¢Ãâ·ÑÓÊÏä3.5GÈÝÁ¿£¬20M¸½¼þ£¡ ____ Christian F. Beckmann University Research Lecturer Oxford University Centre for Functional MRI of the Brain (FMRIB) John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK. [log in to unmask] http://www.fmrib.ox.ac.uk/~beckmann tel: +44 1865 222551 fax: +44 1865 222717 --------------------------------- ÑÅ»¢Ãâ·ÑÓÊÏä3.5GÈÝÁ¿£¬20M¸½¼þ£¡