Dianne,
You want to extract the nodif brain before running FDT, BEDPOST, or any registrations. Additionally you need to make a brain only mask nodif_brain_mask before running either FDR or BEDPOST, if you don't it will try to calculate outside of the brain which will just waste time and produce junk outside. You can use the commandline "bet nodif nodif_brain –m –f .2" to make that mask. You can adjust the last number, .2 to get better extractions (lower is more conservative, higher more liberal). Also registrations will be most successful on extracted brains, as they rely on the edge of the brain to make the alignments.
Peace,
Matt.
From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On Behalf Of Dianne Patterson
Sent: Wednesday, May 23, 2007 1:21 PM
To: [log in to unmask]
Subject: [FSL] Just trying to get this straight
For the fdt pipeline:
1) When I run bedpost, my nodif image should NOT be brain extracted (i.e., it should still have the skull on?)
(what, if anything, will go wrong if no_dif IS brain extracted?)
2) However, when I run registration, my nodif image and my struct should be brain extracted versions.
Thanks,
Dianne
--
Dianne Patterson, Ph.D.
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ERP Lab
University of Arizona
621-3256 (Office)