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Hello,
   
  I have few questions regarding the calculation of brain volume using SIENAX. 
   
  1. Is there any difference in the brain volume between 2 sequences with and without any gap? Does SIENAX estimate the gap area into the total brain volume when there is gap between slices?
   
  2.If we have a T1 weighted sequence, slice with 6mm thickness and 1 mm gap,does it make a difference on the brain volume calculation? 
   
  3. In our studies,we observed that few cases have bad results(brain vol less than 1200ml) even though the parameters of these cases are the same as other cases with good results(vol between 1300ml-1700ml)?what factors affect the calculation of the brain volume? Please let us know. 
   
  Thank You,
  Priya 

       
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