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Hi Torsten, > thanks very much for this. Your script is working nicely. I also checked the > SnMP site, were they actually suggest your approach: > > A two-sided test may be constructed by doing two separate > analyses, one for each tail, at half the chosen significance > level, doubling the resulting p-values. > ( Strictly speaking, this is not equivalent to a rigorous two-sided ) > ( non-parametric test using the permutation distribution of the ) > ( absolute maximum statistic, but it'll do! ) > > Anyway, I am quite happy now - almost :) There is just another thing, in > case I would like to use the cluster-based images as well and combine them > using your script, would that still be valid? I would guess that it would be as valid as for the others... but maybe someone else will comment on this? I've put an updated version of the script here, which should combine the maxc or maxcmass cluster based ones if they're present: http://www.cs.ucl.ac.uk/staff/gridgway/fsl/to-two-tailed Let me know if this doesn't work, I haven't personally tested the cluster-based thresholding. Cheers, Ged.