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Hello, I have DTI data collected with 68 ( 8 no diffusion scans) different directions, with two consecutive scans, that are interleaved to cover the whole brain. In some of them the subject moved from one scan to the other so that when I reconstruct the image there is an obvious shifts between the 2. How can I correct for that. Can I use Flirt with 6 DOF only to register one to the other and then scramble them into one image? Is this transformation going to change the voxel values due to interpolation? thanks for the help Paul Paul Geha M.D. Northwestern University The Feinberg School of Medicine Department of Physiology M211 303 E. Chicago Ave. Chicago, IL 60611 Tel:312-503 2886 Fax: 312-503-5101