Q1: is this a record triglcerides? Have one @196 and seen >200 in pregnancy. As has been said how reliable?
Q2: is it all due to uncontrolled type1 diabetes?Unlikely. LPL defect very likely
Q3: is it worth measuring LPL and apo CII ...etc?Have done a few. Not seen a +ve result yet. Genetics better (? Barts)
Q4: would you admit for hospital care, what is his individual risk of developing acute pncreatitis? No but high risk
How reliable is HDL with such Tg/ Chylomicronaemia?
rgds
A
Ahmed Waise
York Hospital
X5670
-----Original Message-----
From: Clinical biochemistry discussion list [mailto:[log in to unmask]]On Behalf Of Mohammad Al-Jubouri
Sent: 14 May 2007 10:26
To: [log in to unmask]
Subject: Clotted cream serum
31-year-old man, uncontrolled type 1 diabetes (HbA1c 16.4%) with microalbuminuria, attended diabetic OPD and had his lipids checked:
LIPID PROFILE
Cholest. H 34.50 mmol/L
Trigly. H 179 mmol/L
HDL-C H 2.40 mmol/L
LDL-C NA mmol/L
Looked at his sample out of the fridge this morning and it wasn't even full fat milk consistency, it was like a solid clotted cream with no discernible serum above or below the creamy clot.
Q1: is this a record triglcerides?
Q2: is it all due to uncontrolled type1 diabetes?
Q3: is it worth measuring LPL and apo CII ...etc?
Q4: would you admit for hospital care, what is his individual risk of developing acute pncreatitis?
Many thanks
Mohammad
Dr. M A Al-Jubouri
Consultant Chemical Pathologist
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