Hi, i need some help... i am testing FAST but still have some problems. With 3D data: BET and Susan run OK, in FAST after running some time the process is interuppted because of "out of memory". My computer has about 2.5 G and 2 G Swap, thats why i am wondering if this is the real problem...What do you mean? With 2D data (t2_axial): BET and Susan run Ok, in FAST after finishing the program it doesnt return the volume of the all the segmented tissues. I sent you the command line output : /usr/local/fsl/bin/fast -t2 -c 3 -op -e -ov -or -ob -od /root/Desktop/TestDATA_FSL_FA_Completo/THOMAS/1_4/THOMAS_1_4_brain /root/Desktop/TestDATA_FSL_FA_Completo/THOMAS/1_4/THOMAS_1_4_brain 172683.6 609808.6 306740.8 FAST - FMRIB's Automated Segmentation Tool Version 3.53 Image: /tmp/fsl_XOnsuk_THOMAS_1_4_brain T2-weighted image Imagesize : 320 x 320 x 30 Pixelsize : 0.70625 x 0.70625 x 4.2 Initial K-means segmentation... 8 main iterations ... Estimating PVE... Segmentation done successfully! Calculation time 131 seconds! Write segmentation image /tmp/fsl_XOnsuk.fastout/QQQQQ_seg.hdr Successfully! Write restored image /tmp/fsl_XOnsuk.fastout/QQQQQ_restore.hdr Successfully! Write bias field image /tmp/fsl_XOnsuk.fastout/QQQQQ_bias.hdr Successfully! Write probability map of tissue 0 Successfully! Write probability map of tissue 1 Successfully! Write probability map of tissue 2 Successfully! Write PVE image of tissue 0 Successfully! Write PVE image of tissue 1 Successfully! Write PVE image of tissue 2 Successfully! Class: CSF tissue 1 tissue 2 brain percentage Volumes: 0.841463 Finished Thanks for help Thomas