Hi, Can you please help me to understand the commands tbss_1_preproc uses to convert nifti files into analyze format for input into nreg? I would like to convert my files while keeping the native data type (i.e. not rounding to the nearest integer which is what the tbss_1_preproc script does) but simply using: export FSLOUTPUTTYPE=ANALYZE and then multiplying by the necessary factor ($FSLDIR/bin/avwmaths++ $f -mul $FACTOR ${BDIR}/${f}_conv -odt double) does not work. I receive an error when inputing into nreg. However, if I change the file to analyze manually via FSLview (by saving as: *.hdr) and then multiply by the factor the format will be accepted without error by nreg and I can keep my native voxel values. Can you please tell me what fslview is doing differently than the tbss_1_preproc script of: $FSLDIR/bin/avwhd -x $f | sed "s/sform_code .*/sform_code = \'0\'/g" | sed "s/qform_code .*/qform_code = \'0\'/g" > grot.xml $FSLDIR/bin/avwcreatehd grot.xml FAi/${f}_FAi.hdr /bin/rm grot.xml so I that I can change my script accordingly? Thanks so much! Kelly Brown $FSLDIR/bin/avwmaths_16SI FAi/${f}_FAi -ero FAi/${f}_FAi ________________________________________________________________________ Interested in getting caught up on today's news? Click here to checkout USA TODAY Headlines. http://track.juno.com/s/lc?s=198954&u=http://www.usatoday.com/news/front.htm?csp=24