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Hello fellow SPMers, In a recent VBM analysis, I have begun receiving 'Inf' as the threshold when performing FDR correction. I am aware that this means that there is no FDR threshold that can control for q, the FDR value that I have set. What I am unsure of are the implications of this, or what my next step should be. In an exploratory manner, I attempted to use an FDR of .05, .5 and .0005. All three resulted in an 'Inf' threshold. Does this mean that I can't use FDR on this dataset? Why would this be? Obviously FWE and ROI/SVC are alternatives...but are these really my only alternatives? Thanks in advance, Matt Matt Shane Post-doctoral Fellow OLIN Neuropsychiatric Research Center Hartford, CT mshane at harthosp.org