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Hi, If you want to do the final stats in SPM then your only option is to use SnPM (permutation testing in SPM), as the other inference method in SPM (Gaussian field theory) is not valid for data on the TBSS skeleton. So yes you can try to feed the all_FA_skeletonised data into SnPM; I don't know if this will be more memory efficient than randomise - I suspect it may not be, but you can try! Cheers, Steve. On 29 Jan 2007, at 05:31, Kenneth Qiu wrote: > Dear Stephen, > > Thank you for your information. I think I can't afford a new 64-bit > machine and thus plan to carry out subsequent analysis using SPM. > May I ask whether those *nonlinear_hr* images are in MNI space and > ready to perform statistical analysis w/o spatial smoothing? Thank > you very much! > > Best Regards, > Deqiang > > > On 1/28/07, Steve Smith <[log in to unmask]> wrote: Hi, please > see previous posts on this. For this huge analysis you > will need a 64-bit machine, e.g. a 64-bit linux or Mac. > Cheers. > > > On 27 Jan 2007, at 09:41, Kenneth Qiu wrote: > > > Dear FSLexperts, > > > > I'm currently using TBSS to analyze a DTI dataset with 160 images. > > I have been sucessful before the last few steps of tbss_3_postreg. > > When it tried to concatenate all *_nonlinear_hr.* images into one > > 4D image file using avwmerge, the machine reported "out of memory" > > error and the process was killed automatically. With each image > > requiring 14M mem, I caculate that I would need around 2.4 G mem, > > which is bigger than what I have. Therefore, I want to know whether > > there is any way to bypass this obstacle, e.g not using 4D storage. > > > > Any comment is welcome and appreciated! > > > > Regards, > > Deqiang > > > ---------------------------------------------------------------------- > -- > --- > Stephen M. Smith, Professor of Biomedical Engineering > Associate Director, Oxford University FMRIB Centre > > FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK > +44 (0) 1865 222726 (fax 222717) > [log in to unmask] http://www.fmrib.ox.ac.uk/~steve > ---------------------------------------------------------------------- > -- > --- > ------------------------------------------------------------------------ --- Stephen M. Smith, Professor of Biomedical Engineering Associate Director, Oxford University FMRIB Centre FMRIB, JR Hospital, Headington, Oxford OX3 9DU, UK +44 (0) 1865 222726 (fax 222717) [log in to unmask] http://www.fmrib.ox.ac.uk/~steve ------------------------------------------------------------------------ ---