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dear BBers unfortunately, i have posted this ad a couple of times before..... please contact pete about this position if you are interested. his email is [log in to unmask] rick* * *Post-Doctoral Position in Single Particle Analysis.* We are looking for a suitably qualified candidate to fill a position in single particle analysis of transcription complexes at the University of Newcastle, Australia. The position will be initially available for 2 years. Salary from A$57,579 depending on experience. The post-holder will investigate a number of transcription complexes of RNA polymerase using both cryo-electron microscopy and X-ray crystallography, in conjunction with Dr Ben Hankamer at the University of Queensland (http://www.imb.uq.edu.au/), Australia, and Dr Rick Lewis Univeristy of Newcastle, UK (http://www.ncl.ac.uk/camb/), respectively. RNA polymerase is a target for the design of anti-microbials and the structures obtained during the course of the research proposal will serve as templates for the design and synthesis (in collaboration with local colleagues) and the validation by biochemical and structural analyses of novel anti-microbials. Prior experience in cryo-electron microscopy and single particle analysis or X-ray structure determination of large assemblies would be advantageous and training will be provided where necessary. It will be necessary for the post-holder to make several trips to Brisbane, for the EM studies, whilst also participating in an exchange programme with colleagues in Newcastle, UK. Newcastle (Australia) is a coastal city famous for its surfing beaches found ~100 miles (160 km) north of Sydney situated at the mouth of the Hunter river, and adjacent to the world famous Hunter valley wine-growing region. The city enjoys a very pleasant climate all year round. For further information contact Dr Peter Lewis: [log in to unmask] -- Dr. R. J. Lewis Reader in Structural Biology Institute for Cell and Molecular Biosciences Faculty of Medical Sciences Tel: +44 (0)191 222 5482 University of Newcastle Fax: +44 (0)191 222 7424 Newcastle upon Tyne, NE2 4HH, UK Email: [log in to unmask]