I suppose that’s part of the point I’m trying to make. Alteplase has the licence for PE thrombolysis and its unlikely any other company is going to do the trials necessary to get one so using another fibrinolytic is technically prescribing off licence. Locally we’d rather use a drug everyone is familiar with and we use Reteplase for MIs so it makes sense to stick with that. However, this flies in the face of the BTS guidelines and the licensing so we need to make sure we are not going out on a limb. The consultants are generally happy with the idea but it’s the Risk Managers that get twitchy.
Simon
P.S. No, we aren’t thrombolysing strokes yet so I suppose we’ll be on Patricia ‘Ko-Ko’ Hewitt’s list soon enough.
From: Andrew Webster [mailto:[log in to unmask]]
Sent: 04 December 2006 20:15
To: [log in to unmask]
Subject: Re: Thrombolysis for PEs
What would you use for stroke? As only alteplase as far as I am aware has a licence. We use tenecteplase for thrombolysis of MI. Have had to specially stock tpa for PE. Not routinely thrombolysing strokes yet…
Andy Webster
From: Accident and Emergency Academic List [mailto:[log in to unmask]] On Behalf Of JULIAN HUMPHREY
Sent: 04 December 2006 19:55
To: [log in to unmask]
Subject: Re: Thrombolysis for PEs
Hi Simon,
We used it in Barnsley about a month ago for a 'barn door' presentation of a massive PE with in dept cardiac echo proven RV dysfunction. We don't have alteplase in the hospital.
Julian
Simon Dr, Consultant, A&E" <[log in to unmask]> wrote:
Is anyone using Reteplase for thrombolysis of massive PEs rather than
the BTS recommended Alteplase?
Simon
Click here to report this email as spam.