Dear Colleagues I agree with Bruce about if you want "very digested synthesized evidence you have to pay for". However there may be exceptions. As Alison asked about 'Clinicians' I did not specifically write about GPs (although I am one!). But it is difficult to say that MDCONSULT falls into the category of "very digestible evidence". It is a web site that gives many diverse important resources - it is certainly not a database. Evidence based information access falls into four categories 1 -Systems (Computerized Clinical Decision Support Systems) - Ideal /still mostly theoretical 2 - Synopsis - EB journal abstracts 3 - Synthesis - Cochrane reviews 4 - Studies - original articles I think when we refer to synthesized evidence' we are focusing on (2). There have been a few Internet sources that tends to provide more than one source of (2) in one web-interface. OVID interface that is provided FREE to NSW medical personal is one such synthesised resource that provides - Cochrane Library, ACP Journal Club, Clinical Evidence, the Database of Abstracts of Reviews of Evidence (DARE) all though a single search interface. You search using just ONE search box. Even MEDSCAPE is FREE from the CIAP http://www.ciap.health.nsw.gov.au/ site. The same type of resource is now available in the US as SKOLAR http://md.skolar.com/index__.jsp?trg=/jsp/Auth/login__.jsp?url=&query=&category=&resource=&nav=front Maybe in Australia you do not have to pay for most of the synthesise evidence!! - at least in NSW? how about in Victoria? For those of who are in this very informative list from the developing world and who are generalists (GPs/Internal Medicine) some of the resources are FREE and excellent although it will give you only a limited amount of clinical topics to search - e.g. Clinical Evidence (more than 200 topics and 2000 treatments) and PRODIGY (NHS -UK) http://www.prodigy.nhs.uk/ and Bandolier http://www.jr2.ox.ac.uk/Bandolier/ With a little bit of training and even with a dial-up connection from the developing world still PubMed Clinical queries are FREE. http://www.ncbi.nlm.nih.gov/entrez/query/static/clinical.shtml This is the raw material that most evidence is synthesized from (4). Sometimes we have to pay for the Brand-Name (very similar to drugs) and even Super Market items from Woolworth!! I agree if you have the funds - UpToDate and DynaMed are still among the top five -one-stop-shops for the busy clinicians. Watch out for newer community initiatives like MORE http://hiru.mcmaster.ca/More/AboutMore.htm Would like more information from other parts of Australia and other countries (both economically developed and developing) Kumara