Dear Spongers,
I would like to alert you to an article we have recently published:
Abstract in brief: In 1993 we reported a
wound-activated cleavage of isoxazoline alkaloids to aeroplysinin-1 and dienone
in sponges of the genus Aplysina. Based on the results of a series of further
experiments we suggested that this conversion is an activated chemical defense
against microbial infection of the wounded sponge. A recent study, however, introduced
doubt regarding the presence of a wound-activated bioconversion in Aplysina
spp.. This motivated us to carefully reinvestigate the fate of brominated
alkaloids in Aplysina sponges following tissue damage.
I would be very happy to discuss the results of this study with you, so
please feel free to send me any questions or comments regarding our work. If
you don’t have access to the article on the web, please contact me for a
pdf ( [log in to unmask] ).
Moreover, I would like to let you know about some of our earlier
publications and would be happy to send you pdfs and discuss questions about them
with you:
Thoms, C.; Schupp, P. (2005) Biotechnological potential of marine sponges and their
associated bacteria as producers of new pharmaceuticals (part II). Journal
of International Biotechnology Law 2 (6): 257-264.
Thoms, C.; Schupp, P. (2005) Biotechnological potential of marine sponges and their
associated bacteria as producers of new pharmaceuticals (part I). Journal
of International Biotechnology Law 2 (5): 217-220.
Thoms, C.; Wolff, M.; K. Padmakumar; Ebel, R.; Proksch, P.
(2004) Chemical
defense of Mediterranean sponges Aplysina
cavernicola and Aplysina
aerophoba. Zeitschrift für Naturforschung –
Journal of Biosciences 59c (1/2): 113-122.
Thoms, C.; Horn, M.; Wagner, M.;
Hentschel, U.; Proksch, P. (2003) Monitoring microbial diversity and natural product profiles of
the sponge Aplysina cavernicola
following transplantation. Marine Biology 142: 685-692.
Thoms, C.; Ebel, R.; Hentschel, U.;
Proksch, P. (2003) Sequestration
of dietary alkaloids by the spongivorous marine mollusc Tylodina perversa. Zeitschrift
für Naturforschung – Journal of Biosciences 58c (5/6): 426-432.
Looking forward to your comments, questions and pdf requests,
Carsten
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Carsten Thoms, Ph.D.
Postdoctoral Research Associate
UOG Station
Mangilao, GUAM, 96923,
phone: +1-671-735-2696
fax: +1-671-734-6767