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Hi John, as regards to the coregistration: Is the MI-obtimaization function "good enough" to yield reasonable results, if you use a 12-parametric transformation instead of the 6-parametric transformation? > > Actually, SPM's coregistration only does a 6 parameter transform by default, > although it can be coaxed into using 12 - but not via the user interface. bye bye, Siawoosh.