 |
 |
ADVERSE REACTIONS Borage oil may cause such gastrointestinal symptoms as nausea, vomiting, flatulence, diarrhea and bloating. Similar to evening primrose oil, borage oil may precipitate symptoms of undiagnosed complex partial seizures and should be used, if at all, with extreme caution in those with a history of seizure disorders or those taking drugs that lower the seizure threshold, such as aliphatic phenothiazines (e.g., chlorpromazine). INTERACTIONS DRUGS Use of borage oil in schizophrenics who are being treated with certain neuroleptic agents that lower seizure threshold - e.g. aliphatic phenothiazines, such as chlorpromazine - may cause partial complex seizures and possibly other types of seizures. Interactions may occur between borage oil and anticoagulants, such as warfarin, as well as antiplatelet drugs, such as aspirin and NSAIDs. Such interactions may enhance the effects of the anticoagulants and antiplatelet drugs. Manifestations of such interactions, if they were to occur, include nosebleeds, hematuria and increased susceptibility to bruising. Borage oil intake should be stopped if these symptoms occur. NUTRITIONAL SUPPLEMENTS >>>Interactions may occur if borage oil is used with supplements that have antithrombotic activity, such as fish oils. This may be manifested by nosebleeds and increased susceptibility to bruising. HERBS Interactions may occur if borage oil is used with such herbs as garlic (Allium sativum) and ginkgo (Ginkgo biloba). Such interactions may be manifested by nosebleeds and easy bruising. OVERDOSAGE There are no reports of overdosage with borage oil. ------------- Source: http://www.pdrhealth.com/drug_info/nmdrugprofiles/nutsupdrugs/bor_0039.s html Copyright (c)2006 Thomson Healthcare. All Rights Reserved Thomson * PDR --------------- Adrian Smith Leeds University Library