Hello everyone,

 

            I have a problem, typical one I guess, however I was not able to find an answer on FSL list. I have got a very large activation (because I have a very large sample of 40 subjects) which goes in Z up to 22. If, using easythresh, I cut activations below Z=3.1 than I get only one cluster consisting of 26346 voxels and spanning through the entire brain. This is quite useless I think. Is there any way of getting some valuable information out of this? Namely SPM users have nice  Anatomical Automatic Labeling program (http://www.cyceron.fr/freeware/) which is capable of spitting the statistics about how much of the given brain region is being covered by the activation (the template with names of brain regions is taken from ALL map provided with MRIcro). Is there anything comparable available for FSL results. If not how shell I report my data having one huge significant blob ? Rising the Z threshold is not an option as some, otherwise significant regions, would disappear, besides what rationale I would give to such an operation? That I was unable to accurately analyze my data at the p=0.001 ? Going through individual ROIs would be on the other hand extremely tedious.

 

I would appreciate your help very much

 

Best regards