at least one systematic review (duplicated? [1,2]) is available on the subject: its conclusion can be summarized thus: "from the limited data available, annual screening with ultrasound appears to have a sensitivity or detection rate close to 100%. The reported sensitivity of annual CA 125-based screening is about 80% (95% CI 49%-95%)" 1) Bell R, Petticrew M, Sheldon T. The performance of screening tests for ovarian cancer: results of a systematic review. Br J Obstet Gynaecol. 1998 Nov;105(11):1136-47. 2) Bell R, Petticrew M, Luengo S, Sheldon TA. Screening for ovarian cancer: a systematic review. Health Technol Assess. 1998;2(2):i-iv, 1-84. Full text available free of charge at: http://www.hta.nhsweb.nhs.uk/fullmono/mon202.pdf Dr Joseph Watine, PH, AIHP, PharmD, AAHU, EurClinChem Laboratoire de Biologie Polyvalente Centre Hospitalier Général 12027 Rodez Cedex 9 France >From: "Vasikaran, Samuel" <[log in to unmask]> >Reply-To: "Vasikaran, Samuel" <[log in to unmask]> >To: [log in to unmask] >Subject: CA 125 for family screening >Date: Thu, 23 Nov 2006 14:40:10 +0800 > >I am seeking information on the status of CA125 as a screening test for >asymptomatic family members of patients affected by ovarian cancer. Are >there any guidelines on this matter? > >Thank you > >Sam Vasikaran >Royal Perth Hospital >Western Australia _________________________________________________________________ Ten : profite de ton Messenger en illimité sur ton mobile ! http://mobile.live.fr/messenger/ten/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/